Rick, a genius and mad scientist, suddenly returns to his daughter Beth after years of disappearance and runs a science lab in her garage. Rick has a "portal gun" that allows him to travel to various dimensions of the universe. His grandson, Morty, somehow became his assistant, was often dragged into his homemade spacecraft and joined him on all sorts of crazy and exciting cosmic adventures. His daughter and son-in-law were dissatisfied with his madness, but they were helpless against this genius scientist.