One day, a mysterious woman (Jaimie Alexander) appears naked in Times Square, with a strange map-like tattoo on her body, and this woman knows nothing about her past and what happened to her.　　Kurt (Sullivan Stapleton) is a federal agent whose name is tattooed on the body of a mysterious woman, and thus becomes involved in the incident. The boss appoints Kurt as the leader of the crisis response team, and works with colleagues Reid (Rob Brown), Tasha (Audrey Esparza) and others to thoroughly investigate the ins and outs of the incident. As the investigation deepens, an astonishing conspiracy emerges, and in order to stop the criminals, Kurt must work with the mysterious woman, because the tattoos on her body are the key clues to solve the whole case.